Basic Science — World Parkinson Congress Blog

Posts in Basic Science

Single Molecule Array Assay For Phosphorylated Alpha-synuclein Detection In Cerebrospinal Fluid

Single Molecule Array Assay For Phosphorylated Alpha-synuclein Detection In Cerebrospinal Fluid

by Camilla Christina Pedersen, BA, MSc

Basic ScienceCamilla Christina Pedersen, BA, MScOctober 23, 2024Nine, biomarkers, SIMOA, immunoassay, alpha-synucleinComment

What Advice to Give (or Not Give) an Early-Stage Investigator

What Advice to Give (or Not Give) an Early-Stage Investigator

by Malú Gámez Tansey, PhD

Basic ScienceMalu G. Tansey, PhDOctober 8, 2024Nine, Career advice, mentoring, blazing your own trail, open science Comment

Synaptic Telephone

Synaptic Telephone

by Casey Mahoney-Crane, PhD

Basic ScienceCasey Mahoney-Crane, PhDSeptember 26, 2024Nine, Synapses, GBA1, Entorhinal cortex, Parkinson'sComment

CO-OP Feasible And Promising For Helping People With Parkinson’s Achieve Their Goals

CO-OP Feasible And Promising For Helping People With Parkinson’s Achieve Their Goals

by Sarah Davies, Dr. Hannah Gullo and Dr. Emmah Doig

Basic ScienceSarah Davies, Dr. Hannah Gullo and Dr. Emmah DoigSeptember 11, 2024Nine, Parkinson's, GoalsComment

Long-term Effects Of A 6-Month Brisk Walking And Balance Program On Motor Symptoms, Balance And Physical Performance In People With Parkinson Disease

Long-term Effects Of A 6-Month Brisk Walking And Balance Program On Motor Symptoms, Balance And Physical Performance In People With Parkinson Disease

by Margaret KY Mak PhD

Basic ScienceMargaret Mak, PhDAugust 28, 2024Nine, Parkinson's, Walking, Balance, motor progressionComment

Could Mini Antibodies Block Parkinson's Disease Progression?

Could Mini Antibodies Block Parkinson's Disease Progression?

by Anne-Marie Castonguay, PhD

Basic ScienceAnne-Marie Castonguay, PhDAugust 14, 2024Nine, Parkinson's, Monoclonal Antibody, alpha-synucleinComment

Co-pathologies in PD

Co-pathologies in PD

by Jeffrey H. Kordower, PhD

Basic ScienceJeffrey H. Kordower PhDJuly 11, 2024Nine, Parkinson's, Brain, ProteinComment

Unveiling Parkinson's Disease Through The Microscopic Lens

Unveiling Parkinson's Disease Through The Microscopic Lens

by Diana Lázaro, PhD

Basic ScienceDiana Lázaro, PhDJuly 3, 2024Nine, Parkinson's Disease, alpha-synuclein, microscopy, super-resolutionComment

Creating A Human Brain Model To Study Parkinson’s Disease

Creating A Human Brain Model To Study Parkinson’s Disease

by Beatriz Elena Lucumí Villegas, MD

Basic ScienceBeatriz Elena Lucumí Villegas, MDApril 25, 2024Stem Cells, Parkinson's, Organoids, Assembloids, alpha-synuclein, Nine, WPC2023Comment

Replacing The Loss Of Neurons With Super Resistant Ones In Parkinson’s Disease

Replacing The Loss Of Neurons With Super Resistant Ones In Parkinson’s Disease

by Béatrice Morin, MSc

Basic ScienceBéatrice Morin, MScApril 10, 2024Cell replacement therapy, Immunotherapy, Derived monoclonal antibodies, Parkinson's, WPC2023, NineComment

Beyond Color: The Hidden Impact of Neuromelanin In The Brain

Beyond Color: The Hidden Impact of Neuromelanin In The Brain

by Núria Peñuelas, PhD

Basic ScienceNúria Peñuelas, PhDMarch 25, 2024Neuromelanin, Neuronal vulnerability, Preclinical models, Aging, Parkinson's, WPC2023, NineComment

Could Subgrouping Parkinson’s Disease Using Cellular Phenotyping Enable Success at Clinical Trials?

Could Subgrouping Parkinson’s Disease Using Cellular Phenotyping Enable Success at Clinical Trials?

by Toby Burgess PhD Student

Basic ScienceToby Burgess PhD StudentMarch 13, 2024Parkinson, Clinical Trials, Brain, NineComment

Impact of Alpha-Synuclein Pathology on the Blood-Brain Barrier

Impact of Alpha-Synuclein Pathology on the Blood-Brain Barrier

by Kristina Lau, PhD student

Basic ScienceKristina Lau, PhD studentJanuary 17, 2024Brain capillaries, Endothelial activation, Alpha-synuclein pathology, Transporter proteins, Vessel density, Parkinson's, NineComment

Zoom Into Different Flavors of Dopaminergic Neurons

Zoom Into Different Flavors of Dopaminergic Neurons

by Kawai Lee, PhD student

Basic ScienceKawai LeeJanuary 3, 2024Parkinson's, Neurons, Nine Comment

Novel Targets for Parkinson`s Disease Research – The Flcn Gene and its Role in Dopaminergic Neurons

Novel Targets for Parkinson`s Disease Research – The Flcn Gene and its Role in Dopaminergic Neurons

by Julia Obergasteiger

Basic ScienceJulia ObergasteigerNovember 8, 2023Eight, Parkinson's, research, GeneticsComment

The Lysosomes, a Key Player in the Parkinon’s Disease Pathology

The Lysosomes, a Key Player in the Parkinon’s Disease Pathology

by María Sanchiz Calvo PhD Student

Basic ScienceMaría Sanchiz Calvo, PhD StudentOctober 11, 2023eight, Parkinson's, PathologyComment

A New Treatment for Fluctuating and Dyskinetic L-dopa Complications

A New Treatment for Fluctuating and Dyskinetic L-dopa Complications

by Prof David Devos, MD, PhD

Basic ScienceProf David Devos, MD, PhDSeptember 27, 2023Eight, Parkinson's, Brain Comment

Could Changes in Gut Bacteria Contribute to the Development of Parkinson’s Disease in Those with Genetic Risk?

Could Changes in Gut Bacteria Contribute to the Development of Parkinson’s Disease in Those with Genetic Risk?

by Christin Weissleder, PhD

Basic ScienceChristin Weissleder, PhDSeptember 18, 2023parkinsons, WPC2023, gut, eightComment

Good News About Bad Seeds

Good News About Bad Seeds

by David G. Standaert, MD, PhD

Basic ScienceDavid G. Standaert, MD, PhDMay 19, 2023parkinsons, WPC2023Comment

Genetics Has Revolutionized Parkinson’s Research. So What?

Genetics Has Revolutionized Parkinson’s Research. So What?

Mark R Cookson, PhD

Basic ScienceMark R Cookson, PhDJanuary 26, 2023Genetics, Therapies, Inflammation, Microglia, LRRK2, Eight Comment